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    The #1 Gastroenterologist

    Recommended Multi-StrainProbiotics Brand

    VSL#3^ is a gold standardin multi-strain probiotics -
    recommended by experts for quality, consistency,and proven performance.

More Than a Probiotic.A Powerful Medical Food.

Pioneers in Probiotics.Leaders in Gut Health.

VSL#3^ is an ultra-high-potency probiotic medicalfood - and the #1 gastroenterologist-recommended multi-strain probiotics brand.Developed for people with serious gastrointestinalconditions, it's trusted by healthcare professionalsand customers alike for its scientific foundation,clinical credibility, and unwavering quality.

Built on Science.Proven in Practice.

Driven by research - not marketing trends -VSL#3^ is trusted in clinical care for the dietarymanagement of specific gastrointestinalconditions. It continues to set the standard forpotency, consistency, and reliability in probiotic
therapy.

Ultra-High-Potency.Guaranteed.

VSL#3^ products deliver between 112.5 billionand 900 billion live bacteria per serving,depending on the formulation. Unlike manyprobiotics that only promise potency at the timeof manufacture, VSL#3^ guarantees potencythrough expiration when stored as directed.

Clinically Researched Formulas.Real-World Results.

Each VSL#3^ product combines 8 well-characterized probiotic strains from 3 genera tohelp maintain a balanced intestinal microbiota andsupport digestive health. The VSL#3^ family isspecially designed for the dietary management ofirritable bowel syndrome (IBS), ulcerative colitis(UC), and pouchitis.

  • "The best product for IBD. I strongly recommend VSL#3^."

    Dr. Victor Gallo
    Garden City Colon and Rectal Surgery Practice - Garden City,NY

  • "I've had great success in using VSL#3^ post colonoscopy, andespecially so in my IBS and UC patients."

    Dr. William Andy Shaver MDGastroenterologist - Lubbock, TX

  • "I recommend VSL#3^ for maintenance of a healthy gutmicrobiome."

    Dr. George Barret MD
    Founder and Chief of Gastroenterology Beth Israel DeaconessHospital - Milton, MA

    It's What's on the Inside

    Our unique 8-strain formulation is designed so each strain complements the others, helping maintain abalanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.

    • Bifidobacterium

      Bifidobacterium breve, Bifidobacteriumlactis (previously classified as B.infantis), Bifidobacterium lactis(previously classified as B. longum)

    • Lactobacillus

      Lactobacillus acidophilus, Lactobacillushelveticus (previously classified as L.delbrueckii subsp. bulgaricus),Lactobacillus paracasei, Lactobacillus
      plantarum

    • Streptococcus

      Streptococcus thermophilus

      VSL#3^ Capsules: Clean Ingredients. Verified Quality.

      Free From Common Irritants:

      • Dairy-Free
      • Gluten-Free
      • Soy-Free
      • Nut-Free
      • No GMOs
      • Vegan

      Certified for Peace of Mind:

      • FODMAP Friendly Certified
      • Halal Certified
      • Kosher Certified

      Science Over Hype.Purpose Over Promises.

      Built on the legacy of VSL3^ a probiotic trusted by healthcare professionals and recognized for its scientific rigor -VSL^ Probiotics
      continues to advance microbiome science through targeted, high-quality formulations that support both dlinical dietary management and
      everyday wellness.

      • For us, potency isn't a number - it's a principle. Every VSL^Probiotics formulation isdeveloped with meaningful levels of live bacteria, manufactured under controlledconditions, and verified to maintain the labeled CFU count through expiration whenstored as recommended.Potency matters because probiotic function depends onboth the quantity and vitality of live organisms that reach the gut. Even modest lossover time can affect performance, which is why every VSL^ Probiotics product isdesigned and tested to deliver consistent strength from first dose to last.

      • For probiotics to work, live microorganisms must survive both storage and digestionto reach the gut intact. Every VSL^ Probiotics formulation is developed with this inmind - combining carefully selected strains, stability-enhancing formulation design,and packaging to maintain viability from manufacturing through expiration.VSL#3^ ismaintained under strict cold-chain conditions - refrigerated throughout production,storage, and shipping - to help preserve live strains at their intended strength.VSL4^ products are shelf-stable and formulated with acid-resistant capsules that helpprotect probiotic bacteria until they reach the intestinal tract.

      • Our formulations are grounded in science. Each strain is selected for its documentedcharacteristics and ability to contribute meaningfully to a balanced microbiome. Thisapproach draws on years of probiotic research - building on well-studiedformulations and evidence-backed strains to create products designed for specificmicrobiome needs.Across the VSL^ Probiotics family, every formulation follows thesame principle: science guides each step, from strain selection to finished product.This consistent, evidence-based process ensures reliability and quality across thebrand's entire portfolio.

      • VSLR Probiotics builds on the legacy of VSL#3^ - a formulation long trusted byhealthcare professionals for its quality and reliability. That foundation continues toguide how we develop every product in the VSL^ Probiotics family. Our focus remainsthe same: to create formulations grounded in evidence, crafted with precision, andrespected for their consistency - not driven by trends, but by trust earned throughexperience.

        • Works Great!

          Really calms my Gut. I'm so thankful mydoctor recommended this product! Itworks well everyday.

          Verified buyer

        • Best Probiotic ever!

          Can't live without it! Keeps my digestivesystem in its lane and I don't have to beon edge all the time about getting sick...

          Verified buyer

        • Best probiotic ever

          My doctor recommended I should useVSL#3^ probiotics. It has honestlyimproved my quality of life. It is expensi...

          Verified buyer

          Clean Ingredients. Trusted Standards.

          We believe what's not in your probiotic is just as important as what is.

          Dairy Free

          No GMOs

          GlutenFree

          Soy - Free